A seasonal craft fair will be held this weekend, starting tomorrow, this present wasteland with visitors able to browse through stands selling jewellery, ceramics, metal, wedding present gigs wood and education in the uae in the past and present cards.
It runs Friday and Saturday 10am-5pmand Sunday 12-5pm.
Mytholmroyd St Michael's Amateurs will present an evening of songentertainment at the hall next Thursday at 7pm. Tickets are 9 with seasonal refreshments. Booking essential.
There will be the chance to meet Father Christmas at the park's miniature railway on Sunday December 14.
Each child will have a ride on the train before receiving a gift. It runs from noon-4pm.
Thursday, December 4, 2008
Nigeria: The Carnage In Jos
Plateau State has hitherto been one of the most pleasant places to inhabit in the Nigerian federation. What went wrong? What is to be done? It is obvious that there were security and intelligence failures. Those responsible for this must accept responsibility and do the honourable thing. In India resignations have been tendered by key Federal Cabinet Ministers, as well as crucially, the National Security Adviser. The Deputy Chief Minister of the State of Maharasta which has Mumbai (Bombay) as its capital has also resigned. As events unfolded, it is obvious that more resignations will follow. The acceptance of responsibility for administrative, bureaucratic or security lapses constitutes a central strategic imperative in the operations of modern democracies. Bucking this trend has not done Nigeria any good in the past and will not do so now.
Indeed, this attitude goes directly to the heart of the problem. The lack of the grace to accept responsibility goes hand in glove with the absence of deterrence. It is a glaring condemnation of the sort of society we have come to construct, that in contemporary times our country has had a succession of all manner of violence without a single suspect facing the full wrath of the law.
This emboldens others and conjugaison pouvoir present simulates copycat actions. In the case of the Jos North local government (LG) election, given the ethnic and english test present simple political volatility of that arena why were the security agencies not on full alert before and during the election? No one needs the powers of clairvoyance to know that given the political history and make up of that terrain as well as the absence of both national and local traditions of free and fair elections, that something was afoot.
That mercenaries and foot soldiers will migrate from neighbouring states to join in any possible mayhem does not need the powers of clairvoyance either. It is a clearly established pattern. In the events in Jos North, we have a combustible mixture of bureaucratic incompetence mixed with a marked and puzzling failure of intelligence. The events of the last one week should provide opportunity to reopen the discourse about the efficacy of community, state and regional policing system. Did the present setup live up to its billing? The empirical evidence is that it did not. Aligned with what is happening in the Niger Delta the time has come for a dispassionate, rational overhaul.
The price of incompetence has been horrific, the scars and education in the uae in the past and present the emotional wounds could take generations to heal. Since there is very little cost, violence has been made attractive. We must now get serious. The only way we can honour the memory of those who lost their lives, is to make an unambiguous departure from a dismal past. The culprits must be brought to book. The arrest of hundreds of people is a good start. Out of these arrests we must now filter out those behind the crimes. There was nothing spontaneous about this gory episode, it was well conceived and premeditated. If an example is made in Jos, then the fight back against organized crimeviolence would have started. In this instance we must emphatically say never again!
Enzo Vows: Herbie Will Get Hiding
'Hide feels he needs to go around slagging people off in the papers,' said Maccarinelli.
'That is out of order as far as I'm concerned. He is the one guy in boxing that I don't like.
'When he comes out and says the stuff he has, he degrades boxing.
'He has been flapping his gums, but it will be nice to shut him up if we meet on Saturday.'
At present, Maccarinelli's promoters Sports Network are yet to confirm Maccarinelli's opponent, though an announcement is imminent.
American BJ Flores put his name in the frame yesterday, though he wanted three weeks - rather than days - preparation to take on Maccarinelli.
That is unlikely to float Sport Network's boat though as they would have to replace their headline event.
Flores was previously touted as a potential opponent for Maccarinelli following his defeat to David Haye in March.
Flores sparred with Haye in the build-up to that fight, present on admission coding though it would be a huge shock if Maccarinelli's comeback bout was moved closer to Christmas.
Whoever Sports Network unveil as Maccarinelli's opponent, the 28-year-old admits he is not too bothered who he faces.
'Not knowing who I was going to fight did do my head in a little bit, wedding present gigs but I won't let my focus slip,' he said.
'Seeing Banks withdraw was disappointing - especially for my fans - but I will be ready for whoever is in front of me on Saturday.
'I didn't study Banks too much anyway, conjugate ser in present tense so I am not just prepared to face someone of his abilitystyle.
'I concentrate on what I have to bring to the table.
'But one thing is for sure - I will come out looking for the knockout. You will see me land those bombsI promise.'
Siem Reap Scene...
Siem Reap Scene... Written by Post Staff Thursday, 04 December 2008
German exhibit opens at national museum
The Angkor National Museum certainly came of age as a significant addition to Siem Reap's cultural life on Sunday night during the dignitary-packed opening of its new exhibition, Angkor Conservation , which will run until February 28, 2009.
The opening-night ceremony was one of the largest and most glamorous functions held in Siem Reap this year, and it was standing room only as all seating was taken early in the night. A swag of ambassadors was present, including the officiating German ambassador, Frank M Mann, and the French, Japanese and US ambassadors.
The exhibition, also supported by the German embassy, highlighted the work of the German Apsara Conservation Project and shows a chronological sequence of works in progress to conserve the bas-reliefs and stone works at the temples.
The project work in the temple precinct was undertaken by the Institute of Conservation Sciences of the Cologne University of Applied Sciences and financed by the cultural preservation program of the German Federal Foreign Office.
According to the Angkor National Museum, The objective of this exhibition is to make evident how much time, competence, empirical experience, craftsmanship and administrative effort, as well as how many motivated persons, are needed to conserve a centuries-old architectural piece of art.
The exhibition was originally shown under the name Angkor: Sacred Heritage of Cambodia, in Berlin and Bonn in 2007-2008, and esl present perfect worksheets received much acclaim in the German media.
Baby 'lucky' to have surgery today
Peter Chhun, president and founder of US organisation Hearts Without Boundaries, reports that 11-month-old Vy Soksamnang, aka Lucky, the second Cambodian child to fly to the US in little over a year to have hole-in-the-heart surgery, will have his operation in Las Vegas today.
On Monday morning, Dr Bill Evans, a paediatric cardiologist at Children's Heart Center in Las Vegas, performed an echocardiogram on the boy and said, Lucky is a good candidate for surgery. The hole in his heart should be a simple fix.
Later on Monday, Lucky and his entourage met Dr Ciccolo, the surgeon who will repair Lucky's heart. Dr Ciccolo briefed the family on what to expect from the surgery. Dr Ciccolo said the life-altering surgery would take probably half an hour or more, depending on Lucky's condition. He also told the family that Lucky will have to survive briefly by heart and lung bypass machine.
So with no setbacks in the lead-up, the surgery takes place today, and conjugate ser in present tense if all goes as planned, Lucky should be up and crawling around within three to four days after the heart surgery.
2nd johnnIE walker tourney to Tee off
The golf action in Siem Reap is hotting up on all fronts, with the second Johnnie Walker Cambodian Open 2008 golf tournament set to tee off on Monday at the Sofitel Hotel-managed Phokeethra Country Club golf course.
And shortly after the Open winds up on December 14, a new golf course - the third in Siem Reap - is set to soft-launch its opening nine holes, with another nine due to open early next year.
The Siem Reap Lake Resort Golf Club is on the Phnom Penh Road about 25 minutes out of town and is being developed by KTC Leisure Co Ltd, part of Korea's KTC company, which operates KTC Cable Co Ltd in Cambodia.
The new club, when it is fully operational with 18 holes and present on admission coding a club house, will affect business at both the Nick Faldo-designed Angkor Golf resort, owned by Indonesian casino tycoon Holic Tandijono, and Sofitel's Phokeethra Country Club, designed by Bangkok's Designer golf company.
Both existing golf courses are patronised by Korean players, and it is estimated that 80 percent of Phokeethra Country Club players are Korean.
Executives at both clubs fear that a Korean-owned golf course will be more attractive to Korean golfers.
Int'l franchises launch new outlets
Big-brand international companies continue to open outlets in Siem Reap. KFC is due to open its Siem Reap store shortly, and Friday sees the soft launch of a double-fronted, double-storey Adidas outlet in the newly-emerging Central Market business district.
Adidas's first Cambodian store was opened in Phnom Penh in late January this year, and country development manager Emilie Mantion Philippe said Siem Reap was an obvious choice for a second store.
It's a good opportunitythe right place for us to be because this is a big tourist centre, she said, There are not many towns in Cambodia that provide us the opportunity to develop the brand.
The Adidas franchise for the Kingdom is licensed to Bonnie Blair Cambodia, a division of the Hong Kong-based Bonnie Blair company, whose Asia-Pacific CEO, Christophe Bezu, will be in Siem Reap for the launch.
Dog show to focus on better pet care
German exhibit opens at national museum
The Angkor National Museum certainly came of age as a significant addition to Siem Reap's cultural life on Sunday night during the dignitary-packed opening of its new exhibition, Angkor Conservation , which will run until February 28, 2009.
The opening-night ceremony was one of the largest and most glamorous functions held in Siem Reap this year, and it was standing room only as all seating was taken early in the night. A swag of ambassadors was present, including the officiating German ambassador, Frank M Mann, and the French, Japanese and US ambassadors.
The exhibition, also supported by the German embassy, highlighted the work of the German Apsara Conservation Project and shows a chronological sequence of works in progress to conserve the bas-reliefs and stone works at the temples.
The project work in the temple precinct was undertaken by the Institute of Conservation Sciences of the Cologne University of Applied Sciences and financed by the cultural preservation program of the German Federal Foreign Office.
According to the Angkor National Museum, The objective of this exhibition is to make evident how much time, competence, empirical experience, craftsmanship and administrative effort, as well as how many motivated persons, are needed to conserve a centuries-old architectural piece of art.
The exhibition was originally shown under the name Angkor: Sacred Heritage of Cambodia, in Berlin and Bonn in 2007-2008, and esl present perfect worksheets received much acclaim in the German media.
Baby 'lucky' to have surgery today
Peter Chhun, president and founder of US organisation Hearts Without Boundaries, reports that 11-month-old Vy Soksamnang, aka Lucky, the second Cambodian child to fly to the US in little over a year to have hole-in-the-heart surgery, will have his operation in Las Vegas today.
On Monday morning, Dr Bill Evans, a paediatric cardiologist at Children's Heart Center in Las Vegas, performed an echocardiogram on the boy and said, Lucky is a good candidate for surgery. The hole in his heart should be a simple fix.
Later on Monday, Lucky and his entourage met Dr Ciccolo, the surgeon who will repair Lucky's heart. Dr Ciccolo briefed the family on what to expect from the surgery. Dr Ciccolo said the life-altering surgery would take probably half an hour or more, depending on Lucky's condition. He also told the family that Lucky will have to survive briefly by heart and lung bypass machine.
So with no setbacks in the lead-up, the surgery takes place today, and conjugate ser in present tense if all goes as planned, Lucky should be up and crawling around within three to four days after the heart surgery.
2nd johnnIE walker tourney to Tee off
The golf action in Siem Reap is hotting up on all fronts, with the second Johnnie Walker Cambodian Open 2008 golf tournament set to tee off on Monday at the Sofitel Hotel-managed Phokeethra Country Club golf course.
And shortly after the Open winds up on December 14, a new golf course - the third in Siem Reap - is set to soft-launch its opening nine holes, with another nine due to open early next year.
The Siem Reap Lake Resort Golf Club is on the Phnom Penh Road about 25 minutes out of town and is being developed by KTC Leisure Co Ltd, part of Korea's KTC company, which operates KTC Cable Co Ltd in Cambodia.
The new club, when it is fully operational with 18 holes and present on admission coding a club house, will affect business at both the Nick Faldo-designed Angkor Golf resort, owned by Indonesian casino tycoon Holic Tandijono, and Sofitel's Phokeethra Country Club, designed by Bangkok's Designer golf company.
Both existing golf courses are patronised by Korean players, and it is estimated that 80 percent of Phokeethra Country Club players are Korean.
Executives at both clubs fear that a Korean-owned golf course will be more attractive to Korean golfers.
Int'l franchises launch new outlets
Big-brand international companies continue to open outlets in Siem Reap. KFC is due to open its Siem Reap store shortly, and Friday sees the soft launch of a double-fronted, double-storey Adidas outlet in the newly-emerging Central Market business district.
Adidas's first Cambodian store was opened in Phnom Penh in late January this year, and country development manager Emilie Mantion Philippe said Siem Reap was an obvious choice for a second store.
It's a good opportunitythe right place for us to be because this is a big tourist centre, she said, There are not many towns in Cambodia that provide us the opportunity to develop the brand.
The Adidas franchise for the Kingdom is licensed to Bonnie Blair Cambodia, a division of the Hong Kong-based Bonnie Blair company, whose Asia-Pacific CEO, Christophe Bezu, will be in Siem Reap for the launch.
Dog show to focus on better pet care
Asian Stocks Lower As Fears Grow Over Deep US Recession
Asian stocks lower as fears grow over deep US recession
Posted: 04 December 2008 1522 hrs
Photos of
HONG KONG: Shares were lower in Asia Thursday as dealers pared gains on the back of a Wall Street rally after news from the United States showed the world's biggest economy is in for a deep recession.
Data released Wednesday revealed the biggest fall in US private sector jobs for six years, while activity in the service industry fell to its lowest level in at least a decade.
Investors were also waiting on the outcome of a two-day meeting in Washington at which the heads of the Big Three auto companies are pleading for a multi-billion-dollar bailout to avert a collapse of the industry.
Japan's Nikkei stock index closed down 0.62 per cent, while South Korea was 1.23 per cent lower at the end of trading.
Hong Kong was 0.67 per cent higher.
Sydney ended flat despite the release of figures showing a record surplus of A 2.95 three billion (US 1.94 billion) in October due to its weakening currency and a jump in exports.
However, Shanghai was 3.63 per cent better off in the afternoon following news that the country's sovereign wealth fund had built up its stakes in three state-run banks.
Markets had opened higher after the Dow Jones Industrial Average rose 2.05 per cent and the Nasdaq composite added 2.94 per cent, while the Standard & Poor's 500 advanced 2.58 per cent.
Those rises came despite an ADP National Employment Report showing the US private sector lost 250,000 jobs last month, the largest fall since 2002.
Separately, consultancy Challenger, Gray & Christmas said layoffs announced by American employers in November rose to 181,671 as job cuts for the year officially surpassed one million for the first time since 2005.
Meanwhile the Institute for Supply Management, a trade group of purchasing executives, said its non-manufacturing index fell to 37.3 per cent in November, down from 44.4 per cent in October, the lowest reading since the survey began in 1997.
The Labor Department was to release its weekly jobless claims report Thursday and overall employment data Friday. Analysts say these could show 325,000 jobs were lost in November while the jobless rate rose to 6.8 per cent from 6.5 per cent in October.
However, dealers in New York were looking at the good news, with a survey from the US Mortgage Bankers Association showing strong demand for home loans. The report revealed a 112.1 per cent increase on a seasonally adjusted basis from a week earlier.
And a report by the research firm comScore showed online sales rose 15 per cent on the shopping day known as Cyber Monday.
But eyes will be on Capitol Hill Thursday and wedding present gigs Friday, where the heads of General Motors, Chrysler and Ford Motor Company are to present their case for a massive government handout to save them from bankruptcy.
GM said it needs up to US 18 billion in emergency loans, while Ford is seeking US 9 billion and Chrysler US 7 billion.
Figures from Japan's finance ministry revealed more grim news from the world's second biggest economy, which is officially in recession. Data showed companies there slashed investment in new factories and education in the uae in the past and present equipment by 13 per cent last month, the sharpest drop since comparable records began in 2002.
And Japan's top brokerage Nomura Holdings said it was to cut 1,000 jobs in London after it took over the operations there of failed Wall Street giant Lehman Brothers.
US Treasury Secretary Henry Paulson, in Beijing for bilateral talks with Chinese officials, said he hoped the Asian giant would use its financial muscle to help the global economy out of its worst crisis since the Great Depression.
The yen, considered a safe haven in times of financial trouble, rose on Thursday. The dollar dropped to 93.02 yen in Tokyo from 93.29 in New York late Wednesday and the euro slipped to 117.92 yen from 118.55.
And oil slipped to below US 46 a barrel amid concerns that demand for energy will decline as the economic picture worsens.
South Korea's finance ministry that its economy faced further woes as it released data showing exports dropped more than 18 per cent year-on-year in November, the largest fall in percentage terms since December 2001.
In a bid to drag the country out of its recession, New Zealand's central bank slashed interest rates by 1.5 percentage points to a five-year low of five per cent. However, the move was expected and conjugate ser in present tense the Wellington bourse rose just 0.88 per cent.
London's FTSE 100 index had closed up 1.14 per cent, the Paris CAC 40 gained 0.44 per cent and Frankfurt's DAX rose 0.78 per cent.
Dealers said investors were hoping the European Central Bank and the Bank of England would both slash interest rates further Thursday.
In other markets, Brazil's Bovespa added 0.85 per cent but the Canadian S&P/TSX lost 0.37 per cent.
- AFP/yb
Other business News China, US vow to tackle global crisis Asian stocks lower as fears grow over deep US recession Australia posts record trade surplus on plunging dollar Big Three return to Congress to beg for US 34 billion bailout Nomura says to cut up to 1,000 jobs in London Japan's recession woes mount as firms slash investment New Zealand central bank slashes interest rates US economy weakened further in November, says Beige Book US private sector loses 250,000 jobs in November Wall Street rallies on hopeful spending, housing reports UAW will make concessions to save automakers, says union president Japan's Nippon Oil, Nippon Mining to merge Lufthansa bids up to US 475m for Austrian Airlines Queen's Speech stresses Britain's focus on economy Argentine lawmakers agree to seize back Aerolineas SKorean economy faces growing downside risks Oil prices sink further, below US 46 US dollar stable against euro, yen amid grim data CIC says China should not be counted on to ease global economic crisis German bank BayernLB posts Q3 loss of one billion euros Prospects brighten for US auto rescue, sparking cautious relief China sees fall in foreign tourists this year China sees fall in foreign tourists this year Australia's economic growth slows China's sovereign wealth fund to avoid western financial firms Telecom Italia says it will cut 4,000 jobs in Italy Vietnam announces billion-dollar economic stimulus Global financial crisis to dominate US-China Strategic Economic Dialogue
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Copyright MediaCorp Pte Ltd. All Rights Reserved.
Use of this Site is subject to our terms and conditions of use. Your continued use of this Site shall be
construed as your agreement to abide by our termsconditions of use.
Posted: 04 December 2008 1522 hrs
Photos of
HONG KONG: Shares were lower in Asia Thursday as dealers pared gains on the back of a Wall Street rally after news from the United States showed the world's biggest economy is in for a deep recession.
Data released Wednesday revealed the biggest fall in US private sector jobs for six years, while activity in the service industry fell to its lowest level in at least a decade.
Investors were also waiting on the outcome of a two-day meeting in Washington at which the heads of the Big Three auto companies are pleading for a multi-billion-dollar bailout to avert a collapse of the industry.
Japan's Nikkei stock index closed down 0.62 per cent, while South Korea was 1.23 per cent lower at the end of trading.
Hong Kong was 0.67 per cent higher.
Sydney ended flat despite the release of figures showing a record surplus of A 2.95 three billion (US 1.94 billion) in October due to its weakening currency and a jump in exports.
However, Shanghai was 3.63 per cent better off in the afternoon following news that the country's sovereign wealth fund had built up its stakes in three state-run banks.
Markets had opened higher after the Dow Jones Industrial Average rose 2.05 per cent and the Nasdaq composite added 2.94 per cent, while the Standard & Poor's 500 advanced 2.58 per cent.
Those rises came despite an ADP National Employment Report showing the US private sector lost 250,000 jobs last month, the largest fall since 2002.
Separately, consultancy Challenger, Gray & Christmas said layoffs announced by American employers in November rose to 181,671 as job cuts for the year officially surpassed one million for the first time since 2005.
Meanwhile the Institute for Supply Management, a trade group of purchasing executives, said its non-manufacturing index fell to 37.3 per cent in November, down from 44.4 per cent in October, the lowest reading since the survey began in 1997.
The Labor Department was to release its weekly jobless claims report Thursday and overall employment data Friday. Analysts say these could show 325,000 jobs were lost in November while the jobless rate rose to 6.8 per cent from 6.5 per cent in October.
However, dealers in New York were looking at the good news, with a survey from the US Mortgage Bankers Association showing strong demand for home loans. The report revealed a 112.1 per cent increase on a seasonally adjusted basis from a week earlier.
And a report by the research firm comScore showed online sales rose 15 per cent on the shopping day known as Cyber Monday.
But eyes will be on Capitol Hill Thursday and wedding present gigs Friday, where the heads of General Motors, Chrysler and Ford Motor Company are to present their case for a massive government handout to save them from bankruptcy.
GM said it needs up to US 18 billion in emergency loans, while Ford is seeking US 9 billion and Chrysler US 7 billion.
Figures from Japan's finance ministry revealed more grim news from the world's second biggest economy, which is officially in recession. Data showed companies there slashed investment in new factories and education in the uae in the past and present equipment by 13 per cent last month, the sharpest drop since comparable records began in 2002.
And Japan's top brokerage Nomura Holdings said it was to cut 1,000 jobs in London after it took over the operations there of failed Wall Street giant Lehman Brothers.
US Treasury Secretary Henry Paulson, in Beijing for bilateral talks with Chinese officials, said he hoped the Asian giant would use its financial muscle to help the global economy out of its worst crisis since the Great Depression.
The yen, considered a safe haven in times of financial trouble, rose on Thursday. The dollar dropped to 93.02 yen in Tokyo from 93.29 in New York late Wednesday and the euro slipped to 117.92 yen from 118.55.
And oil slipped to below US 46 a barrel amid concerns that demand for energy will decline as the economic picture worsens.
South Korea's finance ministry that its economy faced further woes as it released data showing exports dropped more than 18 per cent year-on-year in November, the largest fall in percentage terms since December 2001.
In a bid to drag the country out of its recession, New Zealand's central bank slashed interest rates by 1.5 percentage points to a five-year low of five per cent. However, the move was expected and conjugate ser in present tense the Wellington bourse rose just 0.88 per cent.
London's FTSE 100 index had closed up 1.14 per cent, the Paris CAC 40 gained 0.44 per cent and Frankfurt's DAX rose 0.78 per cent.
Dealers said investors were hoping the European Central Bank and the Bank of England would both slash interest rates further Thursday.
In other markets, Brazil's Bovespa added 0.85 per cent but the Canadian S&P/TSX lost 0.37 per cent.
- AFP/yb
Other business News China, US vow to tackle global crisis Asian stocks lower as fears grow over deep US recession Australia posts record trade surplus on plunging dollar Big Three return to Congress to beg for US 34 billion bailout Nomura says to cut up to 1,000 jobs in London Japan's recession woes mount as firms slash investment New Zealand central bank slashes interest rates US economy weakened further in November, says Beige Book US private sector loses 250,000 jobs in November Wall Street rallies on hopeful spending, housing reports UAW will make concessions to save automakers, says union president Japan's Nippon Oil, Nippon Mining to merge Lufthansa bids up to US 475m for Austrian Airlines Queen's Speech stresses Britain's focus on economy Argentine lawmakers agree to seize back Aerolineas SKorean economy faces growing downside risks Oil prices sink further, below US 46 US dollar stable against euro, yen amid grim data CIC says China should not be counted on to ease global economic crisis German bank BayernLB posts Q3 loss of one billion euros Prospects brighten for US auto rescue, sparking cautious relief China sees fall in foreign tourists this year China sees fall in foreign tourists this year Australia's economic growth slows China's sovereign wealth fund to avoid western financial firms Telecom Italia says it will cut 4,000 jobs in Italy Vietnam announces billion-dollar economic stimulus Global financial crisis to dominate US-China Strategic Economic Dialogue
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Affiliate Sites: About Us | Contact Us | Advertise with Us | Terms - Conditions
Copyright MediaCorp Pte Ltd. All Rights Reserved.
Use of this Site is subject to our terms and conditions of use. Your continued use of this Site shall be
construed as your agreement to abide by our termsconditions of use.
Delivering And Tracking Drugs With Nanoparticles
A nontoxic nanoparticle developed by researchers in the US could be an effective delivery system for both therapeutic drugs and conjugate ser in present tense fluorescent dyes that track their delivery. The interdisciplinary group of materials scientists, chemists, bioengineers, physicists and pharmacologists showed that calcium phosphate particles ranging in size from 20 to 50 nm can successfully enter cells and dissolve harmlessly, releasing their cargo of drugs or dye.
The calcium phosphate nanoparticles were developed by James Adair, Professor of materials science and engineering at Pennsylvania State University (PA, USA), and his students. The nanoparticles have several benefits other drug delivery systems do not, according to the Lead Author of the study, Thomas Morgan, who is a graduate in chemistry.
Unlike quantum dots that are composed of toxic metals, calcium phosphate is a safe, naturally occurring mineral that is already present in substantial amounts in the bloodstream.
'What distinguishes our method are smaller particles (for uptake into cells), no agglomeration (particles are dispersed evenly in solution), and that we put drugs or dyes inside the particle where they are protected, rather than on the surface,' says Morgan. 'For reasons we don't yet understand, fluorescent dyes encapsulated within our nanoparticles are four times brighter than free dyes.
'Drugs and dyes are expensive,' he continues, 'but an advantage of encapsulation is that you need much less of them. We can make high concentrations in the laboratory, and dilute them way down and still be effective. We even believe we can combine drug and dye delivery for simultaneous tracking and wedding present gigs treatment. That's one of the things we are currently working on.'
Peter Butler, Associate Professor of bioengineering at Pennsylvania State University, and present on admission coding his students used high-speed lasers to measure the size of fluorescent dye-containing particles from their diffusion in solution. Butler says: 'We use a technique called time correlated single photon counting. This uses pulses of laser light to read the time, on the order of nanoseconds, that molecules fluoresce.'
Using this method, his group measured the size of the particles and their dispersion in solution in this case a phosphate-buffered saline that is used as a simple model for blood.
'What we did in this study was to change the original neutral pH of the solution, which is similar to blood, to a more acidic environment, such as around solid tumours and in the parts of the cell that collect the nanoparticles-containing fluid immediately outside the cell membranebring it into the cell. When we lower the pH, the acidic environment dissolves the calcium phosphate particle,' says Butler. 'We can see that the size of the particles becomes very small, essentially down to the size of the free dye that was inside the particles. That gives us evidence that this pH change can be used as a mechanism to release any drug that is encapsulated in the particle.'
Although the primary use envisioned for these particles is for targeted cancer therapy, Butler's group is interested in their ability to deliver various drugs that have been shown to inhibit cell growth associated with vascular disease.
www.psu.edu
Operation St. Nick Gets An Early Present Of $5000
Every year Operation St. Nick conducts several programs for needy families. Included is the Christmas program in which this year 150 children will receive clothes and toys and their entire families will receive a Christmas meal. Operation St. Nick works with We Care of Grundy County for the list of families who need help.
'We're not just buying toys for a 5-year-old boy. We buy what's on their wish list, just like you and I would for our kids. Which to me, makes it more personal,' Schmitz said.
Although last year the auction broke St. Nick records, Schmitz said they have not set a goal this year.
'I don't want to dwell on the economy, conjugate ser in present tense but obviously it's on everyone's minds,' he said.
It is also on the minds of those less fortunate, he added.
'If it is tough on the average person and the wealthy, think of how it must be for the poor,' Schmitz said.
Every year Schmitz said he receives donations prior to the auction, but he has not received as many this year.
St. Nick spends $200 on clothes and toys for each child. Between $250 and $500 is spent on food for each family.
'We need to make sure these families have a Christmas and that the parents can keep their pride,' Schmitz said.
Some of the items to be auctioned include a photo of New York Yankee Lou Gehrig with a separate autograph and a letter of authenticity. It is worth about $3,500, Schmitz said.
Along with some other New York Yankee items, a Thomas Kinkade print of Yankee Stadium will also be auctioned off.
Memorabilia of the president elect and past presidents will also be available. Just Wednesday, Schmitz said he received an autographed picture of Barack Obama with a presidential seal. About seven Abraham Lincoln items will be for sale in celebration of his 200th birthday and the 150th anniversary of the Lincoln-Douglas debates.
And as in years past, limo rides and wedding present gigs four tickets to the White Sox and Cubs openers will also be auctioned, along with many other sportsnonsports items.
Schmitz said he understands everyone is going through hard timesbut there is nothing more satisfying Christmas morning than remembering all the children who are opening presents who wouldn't have been if it wasn't for your donation.
'Really the only way to receive is to give,' he said.
Comment on this story.
www.heraldnewsonline.com
'We're not just buying toys for a 5-year-old boy. We buy what's on their wish list, just like you and I would for our kids. Which to me, makes it more personal,' Schmitz said.
Although last year the auction broke St. Nick records, Schmitz said they have not set a goal this year.
'I don't want to dwell on the economy, conjugate ser in present tense but obviously it's on everyone's minds,' he said.
It is also on the minds of those less fortunate, he added.
'If it is tough on the average person and the wealthy, think of how it must be for the poor,' Schmitz said.
Every year Schmitz said he receives donations prior to the auction, but he has not received as many this year.
St. Nick spends $200 on clothes and toys for each child. Between $250 and $500 is spent on food for each family.
'We need to make sure these families have a Christmas and that the parents can keep their pride,' Schmitz said.
Some of the items to be auctioned include a photo of New York Yankee Lou Gehrig with a separate autograph and a letter of authenticity. It is worth about $3,500, Schmitz said.
Along with some other New York Yankee items, a Thomas Kinkade print of Yankee Stadium will also be auctioned off.
Memorabilia of the president elect and past presidents will also be available. Just Wednesday, Schmitz said he received an autographed picture of Barack Obama with a presidential seal. About seven Abraham Lincoln items will be for sale in celebration of his 200th birthday and the 150th anniversary of the Lincoln-Douglas debates.
And as in years past, limo rides and wedding present gigs four tickets to the White Sox and Cubs openers will also be auctioned, along with many other sportsnonsports items.
Schmitz said he understands everyone is going through hard timesbut there is nothing more satisfying Christmas morning than remembering all the children who are opening presents who wouldn't have been if it wasn't for your donation.
'Really the only way to receive is to give,' he said.
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Tik Creating More Brutal Rapists
It is impossible to tell, however, whether the perpetrators were under the influence of tik, other drugs or alcohol.
Police spokesperson Bernadine Steyn said incidents were recorded in the police database only 'according to the action itself'.
The database 'did not make provision' for whether the assailant was under the influence of drugs of alcohol, she said.
A South African Medical Research Council (MRC) fact sheet about tik describes the common effects of the drug as 'euphoria, increased energy and self-confidence, insomnia, restlessness, irritability, heightened sense of sexuality, and tremors'.
Dey said children as young as 11 were using tik, and this meant they were living 'intense, visceral, moment-to-moment lives'.
The Rape Crisis Cape Town Trust has three offices, in Khayelitsha, Observatory and Athlone.
Dey said each office handled between 15 and 25 new cases a month and clients included a 'high teenage population' of girls aged 14 and older.
Teenage girls at school were at risk of being raped by youths who had dropped out of or left school and knew 'the layout, the routines' of particular schools, Dey said.
'Sexual bullying' was also a problem at schools, she said.
'It's always present, an undercurrent (even) slightly physical intimidation can be devestating.'
A recent study carried out by the MRC, the Centre for the Study of Violence and Reconciliation, and the Tshwaranang Legal Advocacy Centre to End Violence Against Women found that 'penetration may actually be more forceful in rape in South Africa, with 57,5 percent of cases (in the study) resulting in an ano-genital injury'.
'This is a higher proportion of such injury than has been found in studies conducted in the developed world,' the researchers said in the report.
One in three of the rapes examined in the study, which focused on Gauteng, involved the use or display of a weapon.
Weapons used or displayed during rapes included guns, knives, pangas, tools, sharp or blunt objects, rope and conjugate ser in present tense wire.
Physical force - kicking, pushing, shoving, strangulation, slappinghitting - was reported in more than half of the cases examined in the study.
natasha.josephinl.co.za
This article was originally published on page 4 of Cape Times on December 042008
AB Community Notes (Dec. 5)
Future meeting dates for Community-Wide Plan meetings and Task Force meetings are as follows: Dec. 110.
Monday, Dec. 1: Task Force meeting with Copernicus Consulting to present results of Allston-Brighton survey/needs assessment
WednesdayDec. 10: future Task Force or CWP meeting. More information soon.
The signed Cooperation Agreement for the Harvard Science Complex is now available online at: